Reduced levels of opioid analgesics are already detected in human milk. The developmental and health benefits of breastfeeding must be regarded together with the mother's medical need to have for DILAUDID INJECTION and any likely adverse consequences to the breastfed infant from DILAUDID INJECTION or from your fundamental maternal issue.
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If opioid use is needed for a chronic period in the pregnant lady, suggest the individual of the chance of neonatal opioid withdrawal syndrome and ensure that appropriate therapy will likely be readily available
Maternal toxicity was noted in all treatment groups (reduced food items intake and entire body weights in The 2 optimum dose groups). There was no evidence of malformations or embryotoxicity reported.
Aged sufferers (aged 65 several years or more mature) could have greater sensitivity to hydromorphone. In general, use warning when selecting a dosage for an elderly patient, generally starting off within the reduced close of the dosing selection, reflecting the increased frequency of lessened hepatic, renal, or cardiac operate and of concomitant disorder or other drug therapy.
DILAUDID INJECTION can be specified intravenously, although the injection really should be presented pretty slowly and gradually. Fast intravenous injection of opioid analgesics improves the opportunity of Unwanted effects like hypotension and respiratory despair [see DOSAGE AND ADMINISTRATION].
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Keep an eye on patients for indications of website urinary retention or decreased gastric motility when DILAUDID INJECTION is applied concomitantly with anticholinergic medication.
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you need to know that hydromorphone injection may well induce constipation. Check with your doctor about Altering your diet or applying other remedies to circumvent or handle constipation while you are employing hydromorphone injection.
Hydromorphone hydrochloride is a white or almost white crystalline powder that is freely soluble in water, quite somewhat soluble in ethanol (ninety six%), and practically insoluble in methylene chloride.
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